A.Toledano & al.
538
92. Roussotte, F. F.; Gutman, B. A.; Madsen, S. K.; Colby, J. B.; Narr, K. L.; Thompson, P. M.;
Alzheimer's disease Neuroimaging Initiative (ADNI). The apolipoprotein E epsilon 4 allele
is associated with ventricular expansion rate and surface morphology in dementia and
normal aging. Neurobiol Aging
35
, 1309-‐1317 (2014).
93. Mosconi, L. Glucose metabolism in normal aging and Alzheimer's disease: Methodological
and physiological considerations for PET studies. Clin Trans Imaging
1
, doi:
10.1007/s40336-‐013-‐0026-‐y (2013)..
94. Nugent, S.; Tremblay, S.; Chen, K. W.; Ayutyanont, N.; Roontiva, A.; Castellano, C. A.; Fortier,
M.; Roy, M.; Courchesne-‐Loyer, A.; Bocti, C.; Lepage, M.; Turcotte, E.; Fulop, T.; Reiman, E.
M.; Cunnane, S. C. Brain glucose and acetoacetate metabolism: a comparison of young and
older adults. Neurobiol Aging
35
, 1386-‐1395 (2014).
95. Kövari, E.; Herrmann, F. R.; Bouras, C.; Gold, G. Amyloid deposition is decreasing in aging
brains: an autopsy study of 1,599 older people. Neurology
28
, 326-‐331 (2014)
96. Da, X.; Toledo, J. B.; Zee, J.; Wolk, D. A.; Xie, S. X.; Ou, Y.; Shacklett, A.; Parmpi, P.; Shaw, L.;
Trojanowski, J. Q.; Davatzikos, C. Alzheimer's Neuroimaging Initiative. Integration and
relative value of biomarkers for prediction of MCI to AD progression: Spatial patterns of
brain atrophy, cognitive scores, APOE genotype and CSF biomarkers. Neuroimage Clin.
28
,
164-‐173 (2013)
97. Madhyastha, T. M.; Grabowski, T. J. Age-‐related differences in the dynamic architecture of
intrinsic networks. Brain Connect
30
, (en prensa) (2014).
98. Toledano, A.; Álvarez M. I.; Toledano-‐Díaz,, A. Multiple neuronal and glial mechanisms can
be involved in the response to the activation of nicotinic receptors. A. In: Horizons in
Neuroscience Research. Volume 3 Neural Transmissions: Characteristics, Mechanisms and
Malfunctioning, Costa, A. Villalba, E. (Eds). Nova Science Publishers, Inc.; Hauppauge, NY,
pp 1-‐34 (2011).
99. Wolf, D.; Grothe, M.; Fischer, F. U.; Heinsen, H.; Kilimann, I.; Teipel, S.; Fellgiebel, A.
Association of basal forebrain volumes and cognition in normal aging. Neuropsychologia
53
, 54-‐63 (2014).
100. Wirth, M.; Villeneuve, S.; Haase, C. M.; Madison, C. M.; Oh, H.; Landau, S. M.; Rabinovici, G.
D.; Jagust, W. J. Associations between Alzheimer disease biomarkers, neurodegeneration,
and cognition in cognitively normal older people. JAMA Neurol
70,
1512-‐1519 (2013).
101. Jack, C.R Jr.; Wiste, H. J.; Weigand, S. D.; Knopman, D. S.; Lowe, V.; Vemuri, P.; Mielke, M. M.;
Jones, D.T.; Senjem, M. L.; Gunter, J. L.; Gregg, B. E.; Pankratz, V. S.; Petersen, R. C. Amyloid-‐
first and neurodegeneration-‐first profiles characterize incident amyloid PET positivity.
Neurology
12
, 1732-‐1740 (2013).
102. Gold, P. E.; Newman, L. A.; Scavuzzo, C. J,; Korol, D. L. Modulation of multiple memory
systems: from neurotransmitters to metabolic substrates. Hippocampus
23
, 1053-‐1065
(2013).
103. Negash, S.; Wilson, R. S.; Leurgans, S. E.; Wolk, D. A.; Schneider, J. A.; Buchman, A. S.;
Bennett, D. A.; Arnold, S. E. Resilient brain aging: characterization of discordance between
Alzheimer's disease pathology and cognition. Curr Alzheimer Res 10, 844-‐851 (2013).
104. Shulman, J. M.; Chen, K.; Keenan, B. T.; Chibnik, L. B.; Fleisher, A.; Thiyyagura, P.; Roontiva,
A.; McCabe, C.; Patsopoulos, N. A.; Corneveaux, J. J.; Yu, L.; Huentelman, M. J.; Evans, D. A.;
Schneider, J. A.; Reiman, E. M.; De Jager, P. L.; Bennett, D.A. Genetic susceptibility for
Alzheimer disease neuritic plaque pathology. JAMA Neurol
1
, 1150-‐1157 (2013).
105. Cha, J.; Jo, H. J.; Kim, H. J.; Seo, S. W.; Kim, H. S.; Yoon, U., Park, H:, Na, D. L.; Lee, J. M.
Functional alteration patterns of default mode networks: comparisons of normal aging,
amnestic mild cognitive impairment and Alzheimer's disease. Eur J Neurosci
37
, 1916-‐
1924 (2013).
106. Hall, C. N.; Reynell, C.; Gesslein, B.; Hamilton, N. B.; Mishra, A.; Sutherland, B. A.; O'Farrell,
F. M.; Buchan, A. M.; Lauritzen, M., Attwell, D. Capillary pericytes regulate cerebral blood
flow in health and disease. Nature
26
, (en prensa) (2014) doi: 10.1038/nature13165.
107. Verkhratsky, A.; Rodríguez, J. J.; Parpura, V. Neuroglia in ageing and disease. Cell Tissue
Res
21
(en prensa) (2014). doi: 10.1007/s00441-‐014-‐1814-‐z
108. Kilimann, I.; Grothe, M.; Heinsen, H.; Alho, E. J.; Grinberg, L.; Amaro, Jr. E.; Dos Santos, G.
A.; da Silva, R. E.; Mitchell, A. J.; Frisoni, G. B.; Bokde, A. L.; Fellgiebel, A.; Filippi, M.; Hampel,
H.; Klöppel, S.; Teipel, S. J. Subregional Basal Forebrain Atrophy in Alzheimer's Disease: A
Multicenter Study. J Alzheimers Dis
6
(2014). doi:10.3233/JAD-‐132345
