An. Real. Acad. Farm. vol 80 nº 1 2014 - page 42

Elvira López-­‐OlivaMuñoz, EmiliaMuñozMartínez
42
71.
Targher, G., Bertolini, L., Scala, L. y col. 2004. Decreased plasma adiponectin
concentrations are closely associated with nonalcoholic hepatic steatosis in obese
individuals. ClinEndocrinol (Oxf)61, 700-­‐703.
72.
Bertolani, C., Sancho-­‐Bru, P., Failli, P. y col. 2006. Resistin as an intrahepatic cytokine:
overexpressionduring chronic injury and inductionof proinflammatory actions inhepatic
stellatecells. AmJ Pathol 169, 2042-­‐2053.
73.
Marra, F., 2007. Leptin and liver tissue repair: do rodent models provide the answers? J
Hepatol 46, 12-­‐18.
74.
Ota, T., Takamura, T., Kurita, S. y col. 2007. Insulin resistance accelerates a dietary rat
model of nonalcoholic steatohepatitis. Gastroenterology132, 282-­‐293.
75.
Fuchs,M., Sanyal, A.J., 2012. Lipotoxicity inNASH. JHepatol 56, 291-­‐293.
76.
Hotta, K., Yoneda, M., Hyogo, H. y col. 2010. Association of the rs738409 polymorphism in
PNPLA3with liver damage and the development of nonalcoholic fatty liver disease. BMC
MedGenet 11, 172.
77.
Petta, S., Muratore, C., Craxì, A., 2009. Non-­‐alcoholic fatty liver disease pathogenesis: the
present and the future. DigLiverDis41, 615-­‐625.
78.
Horton, J.D., Goldstein, J.L., Brown,M.S., 2002. SREBPs: activators of the completeprogram
of cholesterol and fattyacidsynthesis in the liver. J Clin Invest 109, 1125-­‐1131.
79.
Hua, X.,Wu, J., Goldstein, J.L., Brown, M.S., Hobbs, H.H., 1995. Structure of the human gene
encoding sterol regulatory element binding protein-­‐1 (SREBF1) and localization of
SREBF1andSREBF2 tochromosomes17p11.2and22q13. Genomics25, 667-­‐673.
80.
Shimomura, I., Shimano, H., Horton, J.D. y col. 1997. Differential expressionof exons1aand
1c inmRNAs for sterol regulatory element binding protein-­‐1 in human andmouse organs
andculturedcells. J Clin Invest 99, 838-­‐845.
81.
Foretz, M., Guichard, C., Ferré, P., Foufelle, F., 1999. Sterol regulatory element binding
protein-­‐1c is amajor mediator of insulin action on the hepatic expression of glucokinase
and lipogenesis-­‐relatedgenes. ProcNatl AcadSciUSA96, 12737-­‐12742.
82.
Sato, R., 2010. Sterol metabolismand SREBP activation. Arch BiochemBiophys 501, 177-­‐
181.
83.
Daemen, S., Kutmon, M., Evelo, C.T., 2013. Apathway approach to investigate the function
andregulationof SREBPs. GenesNutr8, 289-­‐300.
84.
Jeon, T.I., Osborne, T.F., 2012. SREBPs: metabolic integrators in physiology and
metabolism. TrendsEndocrinolMetab23, 65-­‐72.
85.
Bennett, M.K., Osborne, T.F., 2000. Nutrient regulation of gene expression by the sterol
regulatory element binding proteins: increased recruitment of gene-­‐specific coregulatory
factors and selective hyperacetylation of histone H3 in vivo. Proc Natl Acad Sci U S A 97,
6340-­‐6344.
86.
Lin, J., Yang, R., Tarr, P.T. y col. 2005. Hyperlipidemic effects of dietary saturated fats
mediated throughPGC-­‐1betacoactivationof SREBP. Cell 120, 261-­‐273.
87.
Li, S., Brown,M.S., Goldstein, J.L., 2010. Bifurcationof insulinsignalingpathway inrat liver:
mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis.
ProcNatl AcadSciUSA107, 3441-­‐3446.
88.
Shimomura, I., Bashmakov, Y., Horton, J.D., 1999. Increased levels of nuclear SREBP-­‐1c
associated with fatty livers in two mouse models of diabetes mellitus. J Biol Chem 274,
30028-­‐30032.
89.
Düvel, K., Yecies, J.L., Menon, S. y col. 2010. Activation of a metabolic gene regulatory
networkdownstreamofmTORcomplex1.Mol Cell 39, 171-­‐183.
90.
Yellaturu, C.R., Deng, X., Park, E.A. y col. 2009. Insulin enhances the biogenesis of nuclear
sterol regulatory element-­‐binding protein (SREBP)-­‐1c by posttranscriptional down-­‐
regulation of Insig-­‐2A and its dissociation from SREBP cleavage-­‐activating protein
(SCAP).SREBP-­‐1c complex. JBiol Chem284, 31726-­‐31734.
91.
Peterson, T.R., Sengupta, S.S., Harris, T.E. y col. 2011. mTOR complex 1 regulates lipin 1
localization tocontrol theSREBPpathway. Cell 146, 408-­‐420.
92.
Willy, P.J., Mangelsdorf, D.J., 1997. Unique requirements for retinoid-­‐dependent
transcriptional activationby theorphanreceptorLXR. GenesDev11, 289-­‐298.
93.
Yoshikawa, T., Shimano, H., Amemiya-­‐Kudo, M. y col. 2001. Identification of liver X
receptor-­‐retinoid X receptor as an activator of the sterol regulatory element-­‐binding
protein1cgenepromoter.Mol Cell Biol 21, 2991-­‐3000.
1...,32,33,34,35,36,37,38,39,40,41 43,44,45,46,47,48,49,50,51,52,...238
Powered by FlippingBook