An. Real. Acad. Farm. vol 80 nº 4 2014 - page 94

734
Induced by 3.;3_-Diindolylmethanethrough Inhibition of F0F1-ATP Synthase in Unicellular
Protozoan Parasite Leishmania donovani. Molecular Pharmacology
74(
5), 1292-1307
(2008).
36. Wang, D.; Jiang, H. U.; Lin, L. V.; Xiuwen, X.I.A..; Jianzhong, L.I.U.; Xiaoyuan, L.I. Enhanced
inhibitory effect of curcumin via reactive oxygen species generation in human
nasopharyngeal carcinoma cells following purple-light irradiation. Oncology Letters
6
(1),
81–85 (2013).
37. Lee, D. S.; Lee, M. K.; Kim, J. H. Curcumin induces cell cycle arrest and apoptosis in human
osteosarcoma (HOS) cells. Anticancer research
29
, 5039-5044 (2009b).
38. Kim, CY.; Le, T. T.; Cheng, J.; Kim, K. Curcumin inhibits adipocyte differentiation through
modulation of mitotic clonal expansion. The Journal of Nutritional Biochemistry
22(
10),
910-920 (2011b).
39. Bertoli, C.; Skotheim, J. M.; De Bruin, R.A.M. Control of cell cycle transcription during G1 and
S phases Nature Reviews. Molecular Cell Biology
14
, 518- 528 (2013).
40. Balasubramanyam, M.; Koteswari, A. A.; Kumar, R. S.; Monickaraj, S. F.; Maheswari, J U.;
Mohan, V. Curcumin-induced inhibition of cellular reactive oxygen species generation,
Novel therapeutic implications. J. Biosci
28,
715–721 (2003).
41. Thayyullathil, F.; Shahanas, C.; Abdulkader, H.; Mahendra, P.; Sehamuddin, G. Rapid
reactive oxygen species (ROS) generation induced by curcumin leads to caspase-
dependent and -independent apoptosis in L929 cells. Free Radical Biology and Medicine
45(
10), 1403–1412 (2008).
42. Yang, J.; Della-Fera, M. A.; Nelson-Dooley, C.; Baile, C. A. Molecular Mechanisms of Apoptosis
Induced by Ajoene in 3T3-L1 Adipocytes. Obesity
14(
3), 388–397 (2006).
43. Funamoto, S.; Anjard, C.; Nellen, W.; Ochiai, H. cAMP-dependent protein kinase regulates
Polysphondylium pallidum development. Differentiation
71
(1), 51-61 (2003).
44. Voet, V.; Pratt. Fundamentals of Biochemistry. Wiley; 2006.
45. Peverelli,E.; Ermetici, F.; Corbetta, S.; Gozzini, E.; Avagliano, L.; Zappa, M.; Bulfamante G.;
Beck-Peccoz, P.; Spada, A.; Mantovani G. PKA regulatory subunit R2B is required for
murine and human adipocyte differentiation. Endocr Connec EC-13-0049, (2006).
46. Wang, J. M; Chao, J. R.; Chen, W.; Kuo, M L.; Yen, J J.; Yang-Yen, H F. The antiapoptotic gene
mcl-1 is up-regulated by the phosphatidylinositol 3-kinase/Akt signaling pathway through
a transcription factor complex containing CREB. Mol. Cell Bio
19
, 6195-7206 (1999).
47. Song, G.; Ouyang, G.; Bao, S. The activation of Akt/PKB signaling pathway and cell survival.
Journal of Cellular and Molecular Medicine
9(
1), 59–71 (2005).
48. Ukkola, O.; Santaniemi, M. Adiponectin: a link between excess adiposity and associated
comorbidities? J. Mol. Med
80
(11), 696–702 (2002)..
49. Bauche, I B.; El Mkadem, S A.; Pottier, A. M.; Senou, M.; Many, M. C.; Rezsohazy, R.; Penicaud,
L.; Maeda, N.; Funahashi, T.; Brichard, S M. Overexpression of adiponectin targeted to
adipose tissue in transgenic mice: impaired adipocyte differentiation. Endocrinology
148
,
1539–1549 (2007).
50. Zhang, B. B.; Zhou, G.; Li, C. AMPK, an emerging drug target for diabetes and the metabolic
syndrome. Cell Metab
5
, 407-416 (2009).
51. Minokoshi, Y.; Kim, Y. B.; Peroni, O. D.; Fryer, L. G.; Müller, C.; Carling. D.; Kahn, BB. Leptin
stimulates fatty-acid oxidation by activating AMP-activated protein kinase. Nature
415
(6869), 339–343 (2002).
52. Taylor, E B.; Hurst, D.; Greenwood, L J.; Lamb, J D.; Cline, T D.; Sudweeks, S N.; Winder, WW.
Endurance training increases LKB1 and MO25 protein but not AMP-activated protein
kinase kinase activity in skeletal muscle. Am. J. Physiol. Endocrinol. Metab
287
(6), E1082-
E1089 (2004).
53. Hardie, D. G.; Ross, F A.; Hawley, S A. AMP-activated protein kinase, a target for drugs both
ancient and modern. Chem Biol
26,19
(10), 1222-1236 (2012).
54. Cantó, C.; Auwerx, J. AMP-activated protein kinase and its downstream transcriptional
pathways. Cell Mol Life Sci
67
(20), 3407-3423 (2010).
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