An. Real. Acad. Farm. vol 80 nº 2 2014 - page 22

CarlosAlonso,Manuel Soto
260
antimonial-­‐sensitive and -­‐resistant strains of
Leishmania donovani
that correlates with
inducible nitric oxide synthase activity and IL-­‐4 generation: evidence formixed Th1-­‐ and
Th2-­‐like responses in visceral leishmaniasis. Journal of Immunology
174
, 7160-­‐7171
(2005).
38 da Silva, R. A.; Tavares, N. M.; Costa, D.; Pitombo, M.; Barbosa, L.; Fukutani, K.; Miranda, J.
C.; deOliveira, C. I.; Valenzuela, J. G.; Barral, A.; Soto,M.; Barral-­‐Netto,M.; Brodskyn, C. DNA
vaccination with KMP11 and Lutzomyia longipalpis salivary protein protects hamsters
against visceral leishmaniasis. ActaTropica
120
, 185-­‐190(2011).
39 Santos, D.M.; Carneiro,M.W.; deMoura, T. R.; Fukutani, K.; Clarencio, J.; Soto,M.; Espuelas,
S.; Brodskyn, C.; Barral, A.; Barral-­‐Netto, M.; de Oliveira, C. I. Towards development of
novel immunization strategies against leishmaniasis using PLGA nanoparticles loaded
with kinetoplastidmembrane protein-­‐11. International Journal of Nanomedicine
7
, 2115-­‐
2127(2012).
40 Santos, D.M.; Carneiro,M.W.; deMoura, T. R.; Soto,M.; Luz, N. F.; Prates, D. B.; Irache, J.M.;
Brodskyn, C.; Barral, A.; Barral-­‐Netto, M.; Espuelas, S.; Borges, V. M.; deOliveira, C. I. PLGA
nanoparticles loaded with KMP-­‐11 stimulate innate immunity and induce the killing of
Leishmania
. Nanomedicine
9
, 985-­‐995(2013).
41 Colmenares, M.; Tiemeyer, M.; Kima, P.; McMahon-­‐Pratt, D. Biochemical and biological
characterizationof theprotective
Leishmaniapifanoi
amastigoteantigenP-­‐8. Infectionand
Immunity
69
, 6776-­‐6784(2001).
42 Whitaker, S. M.; Colmenares, M.; Pestana, K. G.; McMahon-­‐Pratt, D.
Leishmania pifanoi
proteoglycolipid complex P8 induces macrophage cytokine production through Toll-­‐like
receptor4. Infectionand Immunity
76
, 2149-­‐2156(2008).
43 Carrillo, E.; Ahmed, S.; Goldsmith-­‐Pestana, K.; Nieto, J.; Osorio, Y.; Travi, B.; Moreno, J.;
McMahon-­‐Pratt, D. Immunogenicity of the P-­‐8 amastigote antigen in the experimental
model of caninevisceral leishmaniasis. Vaccine
25
, 1534-­‐1543(2007).
44 Colmenares, M.; Kima, P. E.; Samoff, E.; Soong, L.; McMahon-­‐Pratt, D. Perforin and gamma
interferon are critical CD8+ T-­‐cell-­‐mediated responses in vaccine-­‐induced immunity
against
Leishmaniaamazonensis
infection. Infectionand Immunity. 71, 3172-­‐3182(2003).
45 McKean, P. G.; Delahay, R.; Pimenta, P. F.; Smith, D. F. Characterisation of a secondprotein
encoded by the differentially regulated LmcDNA16 gene family of
Leishmania major
.
Molecular andBiochemical Parasitology
85
, 221-­‐231(1997).
46 Flinn, H. M.; Rangarajan, D.; Smith, D. F. Expression of a hydrophilic surface protein in
infective stagesof
Leishm niamajor
.Molecular andBiochemical Parasitology.
65,
259-­‐270
(1994).
47 Jensen, A. T.; Gasim, S.; Moller, T.; Ismail, A.; Gaafar, A.; Kemp, M.; el Hassan, A. M.;
Kharazmi, A.; Alce, T. M.; Smith, D. F.; Theander, T. G. Serodiagnosis of
Leishmania
donovani
infections: assessment of enzyme-­‐linked immunosorbent assays using
recombinant
L. donovani
geneBprotein (GBP) andapeptide sequence of
L. donovani
GBP.
Transactionsof theRoyal Societyof TropicalMedicineandHygiene.
93
, 157-­‐160(1999).
48 Requena, J. M.; Alonso, C.; Soto, M. Evolutionarily conserved proteins as prominent
immunogensduring
Leishmania
infections. ParasitologyToday
16
, 246-­‐250(2000).
49 Probst, P.; Stromberg, E.; Ghalib, H. W.; Mozel, M.; Badaro, R.; Reed, S. G.; Webb, J. R.
Identification and characterization of T cell-­‐stimulating antigens from
Leishmania
by CD4
Tcell expressioncloning. Journal of Immunology
166
, 498-­‐505(2001).
50 Soto,M.; Requena, J.M.; Gomez, L. C.; Navarrete, I.; Alonso, C.Molecular characterizationof
a
Leishmania donovani infantum
antigen identified as histone H2A. European Journal of
Biochemistry
205
, 211-­‐216(1992).
51 Soto, M.; Requena, J. M.; Morales, G.; Alonso, C. The
Leishmania infantum
histone H3
possesses an extremely divergent N-­‐terminal domain. Biochimica et Biophysica Acta.
1219
, 533-­‐535(1994).
52 Soto, M.; Requena, J. M.; Quijada, L.; Perez, M. J.; Nieto, C. G.; Guzman, F.; Patarroyo, M. E.;
Alonso, C. Antigenicity of the
Leishmania infantum
histones H2B and H4 during canine
viscerocutaneous leishmaniasis. Clinical and Experimental Immunology
115
, 342-­‐349
(1999).
53 Souza, A. P.; Soto, M.; Costa, J. M.; Boaventura, V. S.; de Oliveira, C. I.; Cristal, J. R.; Barral-­‐
Netto, M.; Barral, A. Towards amore precise serological diagnosis of human tegumentary
leishmaniasisusing
Leishmania
recombinant proteins. PLoSOne
8
, e66110(2013).
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